About this course
Study basic experimental applied sciences utilized in methods biology, with a specific give attention to RNA sequencing, mass spec-based proteomics, cell move/mass measurement, and cytology imaging dwelling cells.
The principle driver of the sector of methods biology is expertise that enables us to check extra deeply and extra broadly how cells reply to experimental perturbations. This permits us to construct extra detailed quantitative fashions of mobile operate, which might present necessary perception into purposes starting from biotechnology to human illness. This course gives an summary of many present experimental strategies utilized in trendy methods biology, with a give attention to accumulating the quantitative information wanted for computational modeling functions in downstream evaluation. We delve into 4 applied sciences, specifically mRNA sequencing, mass spectrometry-based proteomics, cell move/mass measurement, and reside cell imaging. These strategies are generally utilized in methods biology and vary from genome-wide protection to single-molecule protection, thousands and thousands of cells to single cell, and single timescales to particular person cells. time keys are sampled usually. We not solely current the theoretical underpinnings on which these applied sciences work, but additionally put them in an actual moist lab setting to supply steering on how these strategies are carried out in observe and the way the info The outcomes are analyzed for high quality and content material.
Versatile deadlines Versatile deadlines Reset deadlines to suit your schedule.Shareable Certificates Shareable Certificates Examine for a certificates 100% full 100% on-line Get began now immediately and study by yourself schedule.Lock 2/6 inPrograms Biology and Biotechnology SpecializationAbout 18 hours to finishAccessible languagesSubtitles: French, Portuguese (Europe), Russian, English, Spanish
Syllabus – What you’ll study from this course
Week
Week 1
Introduce
Description right here
Week
Week 2
Deep mRNA sequencing
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Week
Week 3
Proteomics primarily based on mass spectrometry
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Week
Week 4
Midterm examination
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Week
Week 5
Movement and cell quantity measurement for single cell protein ranges and cell destiny
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Week
Week 6
Reside cell imaging for single cell protein dynamics
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Week
Week 7
Combine and interpret datasets with community and dynamic fashions
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Week
Week 8
Closing examination
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